{Reference Type}: Journal Article
{Title}: Risk factors and management of iatrogenic colorectal perforation in diagnostic colonoscopy: a single-center cohort study.
{Author}: Kim A;Kim H;Kim ER;Kim JE;Hong SN;Chang DK;Kim YH;
{Journal}: Scand J Gastroenterol
{Volume}: 59
{Issue}: 6
{Year}: 2024 Jun 21
{Factor}: 3.027
{DOI}: 10.1080/00365521.2024.2316766
{Abstract}: <B>UNASSIGNED: </B>Diagnostic colonoscopy plays a central role in colorectal cancer screening programs. We analyzed the risk factors for perforation during diagnostic colonoscopy and discussed the treatment outcomes.<BR><B>UNASSIGNED: </B>We performed a retrospective analysis of risk factors and treatment outcomes of perforation during 74,426 diagnostic colonoscopies between 2013 and 2018 in a tertiary hospital.<BR><B>UNASSIGNED: </B>A total of 19 perforations were identified after 74,426 diagnostic colonoscopies or sigmoidoscopies, resulting in a standardized incidence rate of 0.025% or 2.5 per 10,000 colonoscopies. The majority (15 out of 19, 79%) were found at the sigmoid colon and recto-sigmoid junction. Perforation occurred mostly in less than 1000 cases of colonoscopy (16 out of 19, 84%). In particular, the incidence of perforation was higher in more than 200 cases undergoing slightly advanced colonoscopy rather than beginners who had just learned colonoscopy. Old age (≥ 70 years), inpatient setting, low body mass index (BMI), and sedation status were significantly associated with increased risk of perforation. Nine (47%) of the patients underwent operative treatment and ten (53%) were managed non-operatively. Patients who underwent surgery were often diagnosed with delayed or concomitant abdominal pain. Perforations of rectum tended to be successfully treated with endoscopic clipping.<BR><B>UNASSIGNED: </B>Additional precautions are required to prevent perforation in elderly patients, hospital settings, low BMI, sedated patients, or by a doctor with slight familiarity with endoscopies (but still insufficient experience). Endoscopic treatment should be actively considered if diagnosis is prompt, abdominal pain absent, and especially the rectal perforation is present.