{Reference Type}: Journal Article
{Title}: Evaluating Fourier-transform infrared spectroscopy with IR Biotyper as a faster and simpler method for investigating the sources of an outbreak of legionellosis.
{Author}: Nakajima N;Jinnai M;Izumiyama S;Kuroki T;
{Journal}: Eur J Clin Microbiol Infect Dis
{Volume}: 43
{Issue}: 5
{Year}: 2024 May 20
{Factor}: 5.103
{DOI}: 10.1007/s10096-024-04781-3
{Abstract}: Fourier-transform infrared (FTIR) spectroscopy using the IR Biotyper and core genome single nucleotide polymorphism (cgSNP) analysis were performed on 12 Legionella isolates associated with an outbreak at a spa house in Kanagawa Prefecture, Japan, and 3 non-outbreak isolates. The discriminative power of FTIR spectroscopy for 48-h incubation conditions of L. pneumophila in this outbreak was lower than cgSNP-based typing but higher than serogroup typing. FTIR spectroscopy could screen outbreak isolates from a group of genetically related isolates and may be useful as an initial typing method in Legionella outbreak investigations.