{Reference Type}: Case Reports
{Title}: Identifying Mixed Dementia With Lewy Bodies and Alzheimer Disease Using Multitracer PET Imaging: A Case Study.
{Author}: Li Q;Wang J;Cui R;Yuan J;
{Journal}: Clin Nucl Med
{Volume}: 49
{Issue}: 4
{Year}: 2024 Apr 1
{Factor}: 10.782
{DOI}: 10.1097/RLU.0000000000005081
{Abstract}: <B>UNASSIGNED: </B>We reported imaging findings with complex signs that were corresponded with both dementia with Lewy bodies (DLB) and Alzheimer disease (AD) in the case of a 78-year-old woman. Initially suspected as DLB due to cognitive and movement issues, diagnostic support included the cingulate island sign on 18 F-FDG PET, positive 131 I-MIBG cardiac scintigraphy, and DAT PET. However, MRI indicated hippocampal atrophy, and 18 F-FDG PET showed hypometabolism in the medial temporal lobe, suggesting the possibility of concomitant AD. Subsequent detection of β-amyloid pathology and tau accumulation in the brain further supported the concurrent presence of AD pathology.