{Reference Type}: Review
{Title}: [Clinical significance and research progress of quantitative hepatitis B virus core antibody measurement].
{Author}: Liu YQ;Zhang C;Zhao H;Wang GQ;
{Journal}: Zhonghua Gan Zang Bing Za Zhi
{Volume}: 32
{Issue}: 1
{Year}: 2024 Jan 20
暂无{DOI}: 10.3760/cma.j.cn501113-20231130-00255
{Abstract}: Hepatitis B virus core antibodies are specific antibodies produced after viral infection that appear early and last for a long time, and its levels in serum are measured by the double-antigen sandwich chemiluminescent microparticle immunoassay method, which has higher sensitivity and specificity, providing new clinical indicators for hepatitis B patients diagnosis, treatment, and drug withdrawal management. This article reviews the clinical significance and research progress of quantitative hepatitis B core antibody measurement and expounds on its research applications and prospects in clinical practice.<BR>乙型肝炎核心抗体是病毒感染后产生的特异性抗体，出现早，持续时间长，利用双抗原夹心化学发光微粒子免疫检测法测量其在血清中的水平，具有更高的灵敏度和特异性，为乙肝患者的诊断、治疗及停药管理提供新的临床指标。本文就乙肝核心抗体定量检测的临床意义及研究进展作综述，阐述其在临床实践中的研究应用及前景。.