{Reference Type}: Case Reports
{Title}: Salivary gland secretory carcinoma presenting as a cervical soft tissue mass: a case report.
{Author}: Mokhles P;Sadeghipour A;Babaheidarian P;Mohebbi S;Keshtpour Amlashi Z;Gharib MH;Ahmadi MS;Khastkhodaei Z;
{Journal}: J Med Case Rep
{Volume}: 18
{Issue}: 1
{Year}: 2024 Feb 5
暂无{DOI}: 10.1186/s13256-024-04364-y
{Abstract}: <B>BACKGROUND: </B>Secretory carcinoma (SC) has been described as a distinct salivary gland tumor in the fourth edition of the World Health Organization (WHO) classification of head and neck tumors. SC is generally considered as a slow-growing low-grade malignant tumor, while several cases have been reported with high-grade features, and even metastases in the literature up until now. In this article, a soft tissue SC case is discussed with high-grade microscopic features and neural invasion. A review of the salivary gland SC cases with aggressive behavior is also debated.<BR><B>METHODS: </B>A 65-year-old Caucasian man presented with a left neck mass for the past six months. The imaging studies demonstrated a very large cystic cervical mass (46 × 23 mm) with papillary projections in the anterolateral aspect of the left neck zone Vb. He underwent left radical neck dissection (level I-V) and was followed up for 12 months with the diagnosis of Secretory carcinoma.<BR><B>CONCLUSIONS: </B>Although SC generally has a good outcome, multiple recurrences and unusual metastases may occur, which should be considered by either the pathologists or clinicians.