{Reference Type}: Journal Article
{Title}: Retrograde amnesia for the stress-induced impairment of extinction: time-dependent and not so forgotten.
{Author}: Briggs JF;McMullen KM;
{Journal}: Learn Mem
{Volume}: 31
{Issue}: 1
{Year}: 2024 Jan-Feb
{Factor}: 2.699
{DOI}: 10.1101/lm.053895.123
{Abstract}: We investigated whether retrograde amnesia for the stress-induced impairment of extinction retrieval shares similar characteristics with original acquisition memories. The first experiment demonstrated that cycloheximide administered shortly after a single restraint stress session alleviated the impairment of extinction retrieval but not when administered following a longer delay (i.e., the amnesia for stress is time-dependent). A second experiment showed that the retrograde amnesia for stress could be alleviated by a second brief exposure to the stressor. These results demonstrating that amnesia for stress shares characteristics similar to original memories are explained using a retrieval-based memory integration model of retrograde amnesia.