{Reference Type}: Journal Article
{Title}: Chiral Truxene-Based Self-Assembled Cages: Triple Interlocking and Supramolecular Chirogenesis.
{Author}: Séjourné S;Labrunie A;Dalinot C;Canevet D;Guechaichia R;Bou Zeid J;Benchohra A;Cauchy T;Brosseau A;Allain M;Chamignon C;Viger-Gravel J;Pintacuda G;Carré V;Aubriet F;Vanthuyne N;Sallé M;Goeb S;
{Journal}: Angew Chem Int Ed Engl
{Volume}: 63
{Issue}: 15
{Year}: 2024 Apr 8
{Factor}: 16.823
{DOI}: 10.1002/anie.202400961
{Abstract}: Incorporating chiral elements in host-guest systems currently attracts much attention because of the major impact such structures may have in a wide range of applications, from pharmaceuticals to materials science and beyond. Moreover, the development of multi-responsive and -functional systems is highly desirable since they offer numerous benefits. In this context, we describe herein the construction of a metal-driven self-assembled cage that associates a chiral truxene-based ligand and a bis-ruthenium complex. The maximum separation between both facing chiral units in the assembly is fixed by the intermetallic distance within the lateral bis-ruthenium complex (8.4 Å). The resulting chiral cavity was shown to encapsulate polyaromatic guest molecules, but also to afford a chiral triply interlocked [2]catenane structure. The formation of the latter occurs at high concentration, while its disassembly could be achieved by the addition of a planar achiral molecule. Interestingly the planar achiral molecule exhibits induced circular dichroism signature when trapped within the chiral cavity, thus demonstrating the ability of the cage to induce supramolecular chirogenesis.