{Reference Type}: Journal Article {Title}: The Rare of the Rarest: Placental Site Trophoblastic Tumor, Epithelioid Trophoblastic Tumor, Atypical Placental Site Nodule. {Author}: Marquina G;Szewczyk G;Goffin F; {Journal}: Gynecol Obstet Invest {Volume}: 89 {Issue}: 3 {Year}: 2024 Jan 27 {Factor}: 2.729 {DOI}: 10.1159/000536494 {Abstract}: BACKGROUND: Epithelioid Trophoblastic Tumor (ETT) and Placental Site Trophoblastic Tumor (PSTT) are two of the rarest GTNs that share certain features at diagnosis and management. Atypical Placental Site Nodule (APSN) is a relatively new entity considered as a premalignant lesion.
OBJECTIVE: The aim of this review was to summarize the main characteristics of each of these entities, their diagnostic features, and their treatment's standard of care including fertility-sparing treatments.
RESULTS: This study provides a thorough review of ETT, PSTT, and APSN.
CONCLUSIONS: The reader will gain an insight view of these rare tumors arising from the intermediate trophoblast.