{Reference Type}: Case Reports
{Title}: A novel approach to full-mouth rehabilitation of dentinogenesis imperfecta type II: Case series with review of literature.
{Author}: Zhang Y;Jin X;Zhang Z;Hu S;Jiang W;Pan H;Zhang L;Fu B;
{Journal}: Medicine (Baltimore)
{Volume}: 103
{Issue}: 4
{Year}: 2024 Jan 26
{Factor}: 1.817
{DOI}: 10.1097/MD.0000000000036882
{Abstract}: <B>BACKGROUND: </B>Dentinogenesis imperfecta (DI) is an autosomal-dominant disorder. The most common clinical manifestations, including obliterated tooth tissues and severe tooth wear, usually lead to tooth extractions. It remains a great challenge for dentists to preserve the residual tooth tissue and establish the esthetics and occlusion of dentitions.<BR><B>METHODS: </B>25-year-old twin sisters, who had suffered from dentinogenesis imperfecta type II for more than 10 years, presented with continuous tooth wear and discomfort from wearing a removable partial denture for more than 3 years.<BR><B>METHODS: </B>Intraoral examination showed extensive tooth wear with enamel exfoliation and typical amber-brown color with an opalescent discoloration. Their panoramic radiographs revealed completely obliterated tooth tissues and severe tooth wear.<BR><B>RESULTS: </B>The dentitions were restored with post-and-core crowns and pin lays after preparing root post paths and pin holes guided by computer-aided design/computer-aided manufacturing (CAD/CAM) procedures, resulting in a successful repair.<BR><B>CONCLUSIONS: </B>Severe tooth wear and tooth tissue obliteration are typical clinical manifestations in DI-affected dentitions, increasing the complexity and difficulty in dental restorations. Early diagnosis and appropriate treatments are essential to achieve a favorable prognosis. CAD/CAM procedures, permitting accurate and effective treatment, possess promising potential in the treatment of DI-affected dentitions.