{Reference Type}: Journal Article
{Title}: Isolation and Characterization of Antimicrobial Metabolites from the Sophora tonkinensis-Associated Fungus Penicillium sp. GDGJ-N37.
{Author}: Huang L;Li Y;Pang J;Lv L;Zhou J;Liang L;He X;Li J;Xu W;Yang R;
{Journal}: Molecules
{Volume}: 29
{Issue}: 2
{Year}: 2024 Jan 10
{Factor}: 4.927
{DOI}: 10.3390/molecules29020348
{Abstract}: Chemical investigation of Penicillium sp. GDGJ-N37, a Sophora tonkinensis-associated fungus, yielded two new azaphilone derivatives, N-isoamylsclerotiorinamine (1) and 7-methoxyl-N-isoamylsclerotiorinamine (2), and four known azaphilones (3-6), together with two new chromone derivatives, penithochromones X and Y (7 and 8). Their structures were elucidated based on spectroscopic data, CD spectrum, and semi-synthesis. Sclerotioramine (3) showed significant antibacterial activities against B. subtilis and S. dysentery, and it also showed most potent anti-plant pathogenic fungi activities against P. theae, C. miyabeanus, and E. turcicum.