{Reference Type}: Case Reports
{Title}: Microlesion Effect Induced by Electrode Implantation in the Posteroventral Globus Pallidus Interna for Severe Dystonic Tics.
{Author}: Permana GI;Morishita T;Tanaka H;Iida H;Fujioka S;Abe H;
{Journal}: Tremor Other Hyperkinet Mov (N Y)
{Volume}: 14
{Issue}: 0
{Year}: 2024
暂无{DOI}: 10.5334/tohm.837
{Abstract}: Tourette syndrome (TS) is a neurologic condition characterized by motor and phonic tics. Dystonic tics, including blepharospasm, are considered atypical or unusual in severe TS.<BR>We report a severe case of TS with facial dystonic tics resembling blepharospasm in which the microlesion effect and a sustained therapeutic effect was observed with bilateral globus pallidus interna (GPi) deep brain stimulation (DBS).<BR>Bilateral GPi DBS can be beneficial for blepharospasm-like tics and severe symptoms of TS. The improvements seen can be explained by the microlesion effect induced by DBS lead placement in the GPi.