{Reference Type}: Journal Article
{Title}: Outcomes of ECMO support with polypropylene membrane during pandemic times: a retrospective cohort study.
{Author}: Valenzuela-Faccini N;Poveda-Henao C;Flórez-Navas C;Pérez-Garzón M;Boada-Becerra N;Mercado-Diaz M;Salcedo P;Robayo-Amortegui H;
{Journal}: BMC Pulm Med
{Volume}: 24
{Issue}: 1
{Year}: 2024 Jan 19
{Factor}: 3.32
{DOI}: 10.1186/s12890-023-02753-5
{Abstract}: <B>BACKGROUND: </B>The SARS-CoV-2 pandemic resulted in shortages of supplies, which limited the use of extracorporeal membrane oxygenation (ECMO) support. As a contingency strategy, polypropylene (PP) oxygenation membranes were used. This study describes the clinical outcomes in patients on ECMO with PP compared to poly-methylpentene (PMP) oxygenation membranes.<BR><B>METHODS: </B>Retrospective cohort of patients in ECMO support admitted between 2020 and 2021.<BR><B>RESULTS: </B>A total of 152 patients with ECMO support were included, 71.05% were men with an average age of 42 (SD 9.91) years. Veno-venous configuration was performed in 75.6% of cases. The PP oxygenation membranes required more changes 22 (63.1%), than the PMP Sorin® 24 (32,8%) and Euroset® 15 (31,9%) (p.0.022). The main indication for membrane change was low oxygen transfer for PP at 56.2%, Sorin® at 50%, and Euroset® at 14.8%. Renal replacement therapy was the most frequent complication with PP membrane in 22 patients (68.7%) Sorin® 25 patients (34.2%), and Euroset® 15 patients (31.9%) (p 0.001) without statistically significant differences in mortality.<BR><B>CONCLUSIONS: </B>PP oxygenation membranes was a useful and feasible strategy. It allowed a greater disponibility of ECMO support for critically ill in a situation of great adversity during the SARS-CoV-2 pandemic.