{Reference Type}: Journal Article
{Title}: Burden of lung cancer attributed to particulate matter pollution in China: an epidemiological study from 1990 to 2019.
{Author}: Fei G;Li H;Yang S;Wang H;Ge Y;Wang Z;Zhang X;Wei P;Li L;
{Journal}: Public Health
{Volume}: 227
{Issue}: 0
{Year}: 2024 Feb 16
{Factor}: 4.984
{DOI}: 10.1016/j.puhe.2023.12.005
{Abstract}: <B>OBJECTIVE: </B>The aim of this study was to examine the disease burden of lung cancer attributable to particulate matter (PM2.5) pollution in China from 1990 to 2019.<BR><B>METHODS: </B>Data from the Global Burden of Disease Study 2019 were used to estimate the disease burden of tracheal, bronchus and lung cancer attributed to PM2.5 over time in China.<BR><B>METHODS: </B>Joinpoint regression models were applied to disability-adjusted life years (DALYs) to assess the time trends and estimate the impact of PM2.5 on the overall disease burden of lung cancer. Furthermore, age-period-cohort models were conducted to assess the relationships between lung cancer DALYs attributed to PM2.5 exposure and age, calendar period and birth cohort trends in China from 1990 to 2019.<BR><B>RESULTS: </B>Lung cancer DALYs attributable to household air pollution from solid fuels decreased with an average annual percent change (AAPC) of 2.9 % per 100,000 population, while those attributable to ambient particular matter pollution (APE) increased (AAPC: -4.7 % per 100,000 population) over the past 30 years. The burden of lung cancer in terms of DALYs in males was higher than in females, and it demonstrated an age-dependent increase. The period and cohort effects also had significant impacts on the DALYs rates of lung cancer attributable to APE, indicating an overall increase in lung cancer DALYs for all age groups in each year.<BR><B>CONCLUSIONS: </B>This study highlights the need for effective strategies to reduce PM2.5 exposure in China, particularly from outdoor sources. Gender differences and age, period and cohort effects observed in the study provide valuable insights into long-term trends of lung cancer burden attributed to PM2.5.