{Reference Type}: Case Reports
{Title}: A Rare Case of Nephrotic Syndrome in the Setting of Sjogren Syndrome-related Cryoglobulinemic Vasculitis.
{Author}: Alexakou Z;Damianaki K;Stambolliu E;Kourniotis D;Mpora M;Petras D;
{Journal}: Saudi J Kidney Dis Transpl
{Volume}: 34
{Issue}: 3
{Year}: 2023 May 1
暂无{DOI}: 10.4103/1319-2442.394001
{Abstract}: Cryoglobulinemia is a rare entity which frequently occurs in the setting of an underlying disease, with chronic hepatitis C virus infections and primary Sjogren syndrome being the most common underlying conditions. Cryoglobulinemic vasculitis (CV) is an immune-mediated type of small-vessel vasculitis with a broad spectrum of specific organ involvement, including renal, pulmonary, peripheral nerve, and cutaneous involvement and variable manifestations that can be life threatening. Moreover, a strong relationship between cryoglobulinemia and CV, with the future development of lymphoma, is well established. We present the case of a 72-year-old Caucasian male referred for nephrotic syndrome and acute renal injury. A diagnosis of Sjogren syndrome-associated CV was made, and he was successfully treated with rituximab and plasma exchange sessions.