{Reference Type}: Case Reports {Title}: An unusual case of endotipsitis: persistent infection and migration to the right atrium of a transjugular intrahepatic portosystemic shunt (TIPS). {Author}: Calpena-Martínez S;Carrasco-Antón N;Cleary-Martín C;Hernández-Estefanía R;Esteban J;Cabello-Úbeda A;Petkova-Saiz E; {Journal}: Eur J Clin Microbiol Infect Dis {Volume}: 43 {Issue}: 3 {Year}: 2024 Mar 17 {Factor}: 5.103 {DOI}: 10.1007/s10096-023-04742-2 {Abstract}: Endotipsitis is an underdiagnosed entity mainly because it requires a high initial level of suspicion. It should be considered in the differential diagnosis of persistent bacteremia in the cirrhotic patient with TIPS. Most cases are treated conservatively with a long-term antibiotherapy, due to the impossibility of surgical removal of the TIPS, except in a liver transplant or autopsy. The patient we present had endotipsitis that manifested as persistent bacteremia with thrombosis of the TIPS. Initially, conservative management with intravenous antibiotherapy was performed; however, due to mechanical complications caused by migration of the original endoprosthesis, it was decided to perform surgery.