{Reference Type}: Case Reports {Title}: A challenging case of sclerosing polycystic adenoma of the parotid gland: a case report and brief review of the latest updates. {Author}: Rashad R;Barakat A; {Journal}: J Histotechnol {Volume}: 47 {Issue}: 2 {Year}: 2024 Jun 15 {Factor}: 1.918 {DOI}: 10.1080/01478885.2023.2299911 {Abstract}: Sclerosing polycystic adenoma (SPA) is a rare neoplastic salivary gland lesion with only about 100 cases reported worldwide so far. The lesion is confused with several malignant and other benign tumors such as apocrine intraductal carcinoma (IC), salivary duct carcinoma (SDC), chronic sclerosing sialadenitis, polycystic dysgenetic disease (PDD), pleomorphic adenoma (PA), acinic cell carcinoma (ACC), and mucoepidermoid carcinoma (MEC). We present a case of SPA for a 23-year-old male patient presenting with a slowly growing parotid mass. Fine needle aspiration (FNA) followed by total excision of the tumor was performed and the picture was consistent with SPA. We discuss the findings of the case and briefly review the literature on SPA.