{Reference Type}: Journal Article
{Title}: Enthesis repair - State of play.
{Author}: Pugliese E;Rossoni A;Zeugolis DI;
{Journal}: Biomater Adv
{Volume}: 157
{Issue}: 0
{Year}: 2024 Feb 22
暂无{DOI}: 10.1016/j.bioadv.2023.213740
{Abstract}: The fibrocartilaginous enthesis is a highly specialised tissue interface that ensures a smooth mechanical transfer between tendon or ligament and bone through a fibrocartilage area. This tissue is prone to injury and often does not heal, even after surgical intervention. Enthesis augmentation approaches are challenging due to the complexity of the tissue that is characterised by the coexistence of a range of cellular and extracellular components, architectural features and mechanical properties within only hundreds of micrometres. Herein, we discuss enthesis repair and regeneration strategies, with particular focus on elegant interfacial and functionalised scaffold-based designs.