{Reference Type}: Journal Article
{Title}: Nanomaterials-Based Field-Effect Transistor for Protein Sensing: New Advances.
{Author}: Aftab S;Li X;Hussain S;Aslam M;Hegazy HH;Abd-Rabboh HSM;Koyyada G;Kim JH;
{Journal}: ACS Sens
{Volume}: 9
{Issue}: 1
{Year}: 2024 01 26
{Factor}: 9.618
{DOI}: 10.1021/acssensors.3c01728
{Abstract}: It is crucial for early stage medical diagnostics to identify disease biomarkers at ultralow concentrations. A wide range of analytes can be identified using low-dimensional materials to build highly sensitive, targeted, label-free, field-effect transistor (FET) biosensors. Two-dimensional (2D) materials are preferable for high-performance biosensing because of their dramatic change in resistivity upon analyte adsorption or biomarker detection, tunable electronic properties, high surface activities, adequate stability, and layer-dependent semiconducting properties. We give a succinct overview of interesting applications for protein sensing with various architectural styles, such as 2D transition metal dichalcogenides (TMDs)-based FETs that include carbon nanotubes (CNTs), graphene (Gr), reduced graphene oxide (rGr), 2D transition-metal carbides (MXene), and Gr/MXene heterostructures. Because it might enable individuals to perform better, this review will be an important contribution to the field of medical science. These achievements demonstrate point-of-care diagnostics' abilities to detect biomarkers at ultrahigh performance levels. A summary of the present opportunities and challenges appears in the conclusion.