{Reference Type}: Journal Article {Title}: Modified STOP-bang questionnaire incorporating morning dry mouth and BMI adjustment in China: a retrospective study of 590 patients. {Author}: Ma X;Zhang C;Feng L;Shen Y;Ma J;Wang G; {Journal}: Expert Rev Respir Med {Volume}: 17 {Issue}: 11 {Year}: 2023 Jul-Dec {Factor}: 4.3 {DOI}: 10.1080/17476348.2023.2292136 {Abstract}: Morning dry mouth (MDM) is a common symptom of Obstructive Sleep Apnea (OSA) yet current OSA screening tools overlook it.
To enhance the specificity of the Stop-Bang questionnaire (SBQ) by adding an MDM symptom.
A retrospective analysis on 590 patients from Peking University First Hospital (2013-2018) suspected of OSA was conducted. They underwent polysomnography. The research incorporated the MDM symptom into SBQ and adjusted the body mass index (BMI) threshold to 28 kg/m2. Predictive parameters were then calculated.
83.1% patients were diagnosed with OSA, with 61.4% reporting MDM. Multivariate regression confirmed MDM significantly influenced Apnea-Hypopnea Index (AHI). Adjusted SBQ with MDM showed a slight decrease in sensitivity but improved specificity, especially when using a BMI threshold of > 28 kg/m2. For AHI ≥ 5 events/h and AHI ≥ 15 events/h, adjusted SBQ with MDM (BMI >28 kg/m2) obtained the highest Youden index.
Incorporating the MDM symptom into SBQ and adjusting the BMI threshold enhances the diagnostic specificity for OSA.