{Reference Type}: Journal Article
{Title}: A comparative study of cyanoacrylate-based tissue adhesive and surgical sutures on marginal flap stability following coronally advanced flap.
{Author}: Pabst A;Becker P;Kuchen R;Schumann S;Kasaj A;
{Journal}: Clin Oral Investig
{Volume}: 28
{Issue}: 1
{Year}: 2023 Dec 20
{Factor}: 3.606
{DOI}: 10.1007/s00784-023-05390-8
{Abstract}: <B>BACKGROUND: </B>The present study evaluated the biomechanical characteristics of cyanoacrylate-based tissue adhesive (TA) compared to surgical sutures in coronally advanced flap (CAF) procedures using an ex-vivo model.<BR><B>METHODS: </B>Thirty-six half-pig mandibles were divided into three groups, n=12 each: (I) CAF fixed with sutures (sling and tag suture technique), (II) CAF fixed with TA, and (III) CAF fixed with sutures and TA. At mandibular premolars, gingival recession defects extending 3 mm apical to the cemento-enamel junction (CEJ) were created. CAF procedures were performed using a split-full-split approach, with coronal advancement of the flap to 1 mm above the marked CEJ and stabilization according to the respective groups I-III. Marginal flap stability against pull-of forces (maximum tensile force) was measured with a universal material testing machine until the CEJ became visible.<BR><B>RESULTS: </B>The comparison between groups I-III demonstrated a significantly increased maximum tensile force for the TA (II) compared to the suture group (I) (p<0.001). A significantly increased maximum tensile force was found for the suture and TA (III) compared to the suture group (I) (p<0.001). There was also a significantly increased maximum tensile force in the suture and TA (III) compared to the TA group (II) (p<0.001).<BR><B>CONCLUSIONS: </B>The results suggest that cyanoacrylate-based TA can increase marginal flap stability compared to sutures in CAF procedures.<BR><B>CONCLUSIONS: </B>Cyanoacrylate-based TA can be considered a useful and valuable adjunct to conventional suturing techniques in periodontal plastic surgery, especially in cases where high flap stability is required. The results of this ex-vivo study can only be transferred to the clinical situation with limitations. Clinical long-term follow-up data must be generated.