{Reference Type}: Case Reports
{Title}: Priapism in a 31-Year-Old Male With Paranoid Schizophrenia.
{Author}: Espiridion ED;Saxena S;
{Journal}: Cureus
{Volume}: 15
{Issue}: 11
{Year}: 2023 Nov
暂无{DOI}: 10.7759/cureus.48978
{Abstract}: Priapism is a painful and emergent side effect that has been linked to some antipsychotics and other psychiatric medications, most often trazodone. This is thought to be due to some level of alpha-1 adrenergic blockade by these medications. Aripiprazole is an atypical antipsychotic with notably weak alpha-1 adrenergic antagonism. Thus, we report on a unique case of aripiprazole-induced priapism in a patient with schizophrenia and recurrent episodes of antipsychotic-induced priapism. This study offers insight into the potential mechanism of aripiprazole-induced priapism and offers alternative medications, such as olanzapine and lumateperone, to treat the patient's ongoing psychotic disorder.