{Reference Type}: Journal Article
{Title}: Efficacy of intratympanic steroid therapy for severe and profound sudden sensorineural hearing loss.
{Author}: Aliyeva A;Edizer DT;
{Journal}: Am J Otolaryngol
{Volume}: 45
{Issue}: 2
{Year}: 2024 Mar-Apr 10
{Factor}: 2.873
{DOI}: 10.1016/j.amjoto.2023.104170
{Abstract}: <B>BACKGROUND: </B>Intratympanic steroids (ITS) in treating sudden sensorineural hearing loss (SSNHL) have become more widespread.<BR><B>OBJECTIVE: </B>This study investigates whether ITS treatment provides additional benefits when combined with systemic steroids (SS) in patients with severe and profound SSNHL.<BR><B>METHODS: </B>Patients diagnosed with severe and profound SSNHL were divided into two groups: SS group and SS combined with ITS group. Pure-tone audiometry was performed before and three months after treatment completion. The pure-tone average (PTA), frequency-specific hearing gains, and average values were compared between the groups.<BR><B>RESULTS: </B>The study included 57 patients (27 SS, 30 ITS), with a mean age of 50.09 ± 15.56. Before treatment: SS PTA 84.40 ± 15 dB HL, ITS 87.50 ± 9.38 dB HL (p = 0.36). After treatment: SS 62.2 ± 23.13 dB HL, ITS 65.17 ± 12.19 dB HL (p = 0.55). Average hearing gain: SS 22.19 ± 13.81 dB HL, ITS 22.33 ± 12.24 dB HL (p = 0.96). Frequency-specific gains were similar (p > 0.05). SS group: 12 slight improvement, 10 no improvement, 3 partial, 2 complete recovery. ITS group: 23 slight improvement, 6 no improvement, 1 partial.<BR><B>CONCLUSIONS: </B>In our study, combining ITS with SS treatment did not provide additional benefits in treating severe and profound SSNHL.