{Reference Type}: Journal Article
{Title}: Subjective Cognitive and Communicative Complaints and Health-Related Quality of Life in Parkinson's Disease with and without Mild Cognitive Impairment.
{Author}: Jaramillo-Jimenez A;Bocanegra Y;Buriticá O;Pineda Salazar DA;Moreno Gómez L;Tobón Quintero CA;Aguirre-Acevedo DC;Sierra Castrillon M;Vasquez D;Velez-Hernandez JE;Borda MG;García-Cifuentes E;Aguillón DF;Madrigal-Zapata L;Aarsland D;Lopera F;
{Journal}: Rev Colomb Psiquiatr (Engl Ed)
{Volume}: 52
{Issue}: 4
{Year}: 2023 Oct-Dec
暂无{DOI}: 10.1016/j.rcpeng.2023.11.004
{Abstract}: <B>BACKGROUND: </B>Mild Cognitive Impairment (MCI) is common in Parkinson's Disease (PD). Few studies have compared the Health-Related Quality of Life (HRQoL) in patients with and without MCI due to PD (PD-MCI), and its correlation to patients' subjective cognitive and communicative difficulties has not been explored.<BR><B>OBJECTIVE: </B>We aimed to compare HRQoL in PD-MCI and PD without MCI (PD-nMCI), and explore its possible relationship to subjective cognitive and communicative complaints.<BR><B>METHODS: </B>We included 29 PD-nMCI and 11 PD-MCI patients. The HRQoL was assessed with the Parkinson's Disease Questionnaire-39 (PDQ-39): its Cognition dimension was used as a measure of subjective cognitive complaints, its Communication dimension for subjective communicative complaints, and the summary index (PDQ-39 SI) as an indicator of HRQoL. Non-parametric partial correlations between the Cognition and Communication dimensions, and the adjusted PDQ-39 SI were conducted.<BR><B>RESULTS: </B>PD-MCI patients had greater subjective cognitive and communicative complaints and worse HRQoL than PD-nMCI patients. In the PD-MCI group, both subjective cognitive and communicative complaints exhibited significant direct correlations with the adjusted HRQoL scores.<BR><B>CONCLUSIONS: </B>HRQoL seems to be affected in PD-MCI, and it might be influenced by greater subjective cognitive and communicative complaints. Including patient-reported outcome measures of HRQoL, and providing cognitive and speech rehabilitation, as well as psychotherapeutic strategies to face these deficits can enhance the patient-centred approach in PD.