{Reference Type}: Journal Article {Title}: Abdominal circumference growth velocity as a predictor of adverse perinatal outcomes in small-for-gestational-age fetuses. {Author}: Rodriguez-Sibaja MJ;Villa-Cueva A;Ochoa-Padilla M;Rodriguez-Montenegro MS;Lumbreras-Marquez MI;Acevedo-Gallegos S;Gallardo-Gaona JM;Copado-Mendoza Y; {Journal}: J Matern Fetal Neonatal Med {Volume}: 36 {Issue}: 2 {Year}: 2023 Dec {Factor}: 2.323 {DOI}: 10.1080/14767058.2023.2262077 {Abstract}: UNASSIGNED: To assess the predictive value of abdominal circumference growth velocity (ACGV) between the second and third trimesters to predict adverse perinatal outcomes in a cohort of small-for-gestational-age fetuses without evidence of placental insufficiency (i.e. fetal growth restriction).
UNASSIGNED: This is a single-center retrospective cohort study of all singleton pregnancies with small-for-gestational-age fetuses diagnosed and delivered at a quaternary institution. Crude and adjusted odds ratios (ORs) and corresponding confidence intervals (CIs) were calculated via logistic regression models to assess the potential association between abnormal ACGV (i.e. ≤10th centile) and adverse perinatal outcomes defined as a composite outcome (i.e. umbilical artery pH <7.1, 5-min Apgar score <7, admission to the neonatal intensive care unit, hypoglycemia, intrapartum fetal distress requiring expedited delivery, and perinatal death). Furthermore, the area under the receiver-operating characteristic curve (AUC) of three logistic regression models based on estimated fetal weight and ACGV for predicting the composite outcome is also reported.
UNASSIGNED: A total of 154 pregnancies were included for analysis. The median birthweight for the cohort was 2,437 g (interquartile range [IQR] 2280, 2635). Overall, the primary composite outcome was relatively common (29.2%). In addition, there was a significant association between abnormal ACGV and adverse perinatal outcomes (OR 3.37, 95% CI 1.60, 7.13; adjusted OR 4.30, 95% CI 1.77, 10.49). Likewise, the AUC for the ACGV was marginally higher (0.64) than the estimated fetal weight (0.54) and ACGV + estimated fetal weight (0.54). Still, no significant difference was detected between the curves (p = 0.297).
UNASSIGNED: Our results suggest that an ACGV below the 10th centile is a risk factor for adverse perinatal outcomes among small-for-gestational-age fetuses.