{Reference Type}: Journal Article
{Title}: Neuroimaging manifestations of paediatric histiocytoses.
{Author}: Tan HEI;Lakshmanan R;Warne R;Walwyn T;Roebuck D;
{Journal}: J Med Imaging Radiat Oncol
{Volume}: 0
{Issue}: 0
{Year}: 2023 Nov 14
{Factor}: 1.667
{DOI}: 10.1111/1754-9485.13602
{Abstract}: Histiocytoses are rare multi-system disorders marked by abnormal histiocyte cell proliferation, affecting children with diverse clinical presentations. Classified into five groups in 2016, including Langerhans-related (L), cutaneous (C), malignant (M), Rosai-Dorfman disease (R) and haemophagocytic lymphohistiocytosis (H), newer entities such as ALK-positive histiocytosis have also emerged, heralding the era of molecular (sub)classification. Common entities include Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD), Rosai-Dorfman disease (RDD) and haemophagocytic lymphohistiocytosis (HLH). This pictorial essay aids radiologists in recognising and differentiating paediatric histiocytoses based on unique neuroimaging features.