{Reference Type}: Journal Article
{Title}: Long-term effects of surgically corrected menstrual outflow obstruction: A case-control study.
{Author}: Martens L;Spath MA;van Beek MA;Willemsen WNP;Kluivers KB;
{Journal}: Int J Gynaecol Obstet
{Volume}: 165
{Issue}: 1
{Year}: 2024 Apr 14
{Factor}: 4.447
{DOI}: 10.1002/ijgo.15237
{Abstract}: <B>OBJECTIVE: </B>To enhance evidence-based knowledge on long-term sequalae in patients with surgically corrected obstructing Müllerian anomalies.<BR><B>METHODS: </B>This long-term case-control study included patients with menstrual outflow obstruction due to congenital anomalies of the uterus or vagina, who were at least 18 years old, and for whom 2 years had elapsed since the first surgery at the start of this study. The control group consisted of women without current gynecological problems. Patients underwent a surgical correction at the Radboud University Medical Center Nijmegen between 1980 and 2013. Of 78 patients approached, 38 (49%) were included in this study. The control group consisted of 54 females. The main outcome measures were pain and health state. The following questionnaires were used: Visual Analogue Scale pain scores, European Quality of Life-5 Dimensions questionnaire (EQ-5D-3L) and the adapted Endometriosis Health Profile questionnaire (EHP-30).<BR><B>RESULTS: </B>Patients had higher actual and maximum abdominal pain scores compared with controls (11 vs 0 [P = 0.007] and 48 vs 21 [P = 0.035], respectively). Based on the EQ-5D-3L scores, patients had more pain and discomfort (P = 0.005), more mood problems (P = 0.023), and a poorer subjective health state (P = 0.002) and self-rated health state (P = 0.031). Based on the EHP-30, patients had a significant poorer self-rated health state on four out of five subscales.<BR><B>CONCLUSIONS: </B>In this study, following surgically corrected menstrual obstruction, patients had statistically significant higher abdominal pain scores and a poorer self-rated health state compared with controls.