{Reference Type}: Journal Article {Title}: Non-syndromic and Syndromic Severe Acne in Adolescent Patients. {Author}: Yen H;Lalor L; {Journal}: Med Clin North Am {Volume}: 108 {Issue}: 1 {Year}: 2024 Jan {Factor}: 6.912 {DOI}: 10.1016/j.mcna.2023.05.014 {Abstract}: Acne is a common skin disorder in adolescents. However, severe acne that is persistent and refractory to conventional treatment or has other associated symptoms should raise suspicion for non-syndromic or syndromic acne.