{Reference Type}: Case Reports
{Title}: A Rare Case of Lambert-Eaton Myasthenia Syndrome Associated with Non-Hodgkin's Lymphoma: A Case Report and Review of the Literature.
{Author}: Abu-Tineh M;Alamin MA;Aljaloudi E;Alshurafa A;Garcia-Cañibano B;Taha RY;Elkourashy SA;
{Journal}: Case Rep Oncol
{Volume}: 16
{Issue}: 1
{Year}: 2023 Jan-Dec
暂无{DOI}: 10.1159/000534557
{Abstract}: <B>UNASSIGNED: </B>Lambert-Eaton myasthenia syndrome (LEMS) is a rare autoimmune disorder characterized by autoantibodies targeting presynaptic neuromuscular junctions. It results in muscle weakness and autonomic dysfunction. LEMS can be idiopathic or associated with neoplastic diseases, often small-cell lung cancer. This case report describes a rare instance of paraneoplastic LEMS in a man with non-Hodgkin lymphoma.<BR><B>UNASSIGNED: </B>A 57-year-old male with non-Hodgkin lymphoma presented with progressive muscle weakness, diminished reflexes, and autonomic symptoms. Diagnosis revealed LEMS with autoantibodies against voltage-gated calcium channels. Immunosuppressive therapy and lymphoma treatment led to significant improvement in his condition.<BR><B>UNASSIGNED: </B>This case highlights the rare occurrence of paraneoplastic LEMS in a patient with non-Hodgkin lymphoma. Recognition and timely management of LEMS alongside lymphoma treatment can lead to significant clinical improvement, emphasizing the need for increased awareness of such complex associations.