{Reference Type}: Journal Article
{Title}: A Practical Guide to Sigma-1 Receptor Positron Emission Tomography/Magnetic Resonance Imaging: A New Clinical Molecular Imaging Method to Identify Peripheral Pain Generators in Patients with Chronic Pain.
{Author}: Shen B;Yoon D;Castillo J;Biswal S;
{Journal}: Semin Musculoskelet Radiol
{Volume}: 27
{Issue}: 6
{Year}: 2023 Dec
{Factor}: 1.675
{DOI}: 10.1055/s-0043-1775744
{Abstract}: Accurately identifying the peripheral pain generator in patients with chronic pain remains a major challenge for modern medicine. Millions of patients around the world suffer endlessly from difficult-to-manage debilitating pain because of very limited diagnostic tests and a paucity of pain therapies. To help these patients, we have developed a novel clinical molecular imaging approach, and, in its early stages, it has been shown to accurately identify the exact site of pain generation using an imaging biomarker for the sigma-1 receptor and positron emission tomography/magnetic resonance imaging. We hope the description of the work in this article can help others begin their own pain imaging programs at their respective institutions.