{Reference Type}: Case Reports
{Title}: Hematopoietic stem cell transplantation from an infected SARS-CoV2 haploidentical donor: A case report.
{Author}: Chen X;Ma Q;Pang A;Yang D;Liang C;Liu Q;Liu X;Zheng X;Jiang E;Han M;Feng S;
{Journal}: IDCases
{Volume}: 34
{Issue}: 0
{Year}: 2023
暂无{DOI}: 10.1016/j.idcr.2023.e01913
{Abstract}: UNASSIGNED: We report a case of an adult hematopoietic stem cell donor who developed active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the donation of stem cells, the final transplantation was successfully completed without SARS-CoV-2 transmission.
UNASSIGNED: We report on a 34-year-old female diagnosed with acute lymphoblastic leukemia who underwent hemiploid hematopoietic stem cell transplantation (HSCT). Both patient and donor received three doses of inactivated SARS-CoV-2 vaccine before transplantation. PB-HSC was collected by the donor during the process of infection with SARS-CoV-2 (mild), and the patient did not show symptoms related to SARS-CoV-2 after transplantation. Nucleic acid and antigen were negative in regular tests.
UNASSIGNED: In the context of the current Omicron epidemic and high vaccination rate in the population, it is feasible to receive PB-HSC from infected donors even for immunocompromised patients. This also provides some references for our later donor selection.