{Reference Type}: Journal Article
{Title}: The Association Between Choroidal Thickness and Meniere's Disease: A Cross-Sectional Study.
{Author}: Akbarpour M;Jalali MM;Alizadeh Y;Nemati S;Akbari M;Dourandeesh M;
{Journal}: Laryngoscope
{Volume}: 134
{Issue}: 4
{Year}: 2024 Apr 2
{Factor}: 2.97
{DOI}: 10.1002/lary.31136
{Abstract}: <B>OBJECTIVE: </B>To evaluate and compare choroidal thickness (CT) between patients with Meniere's disease (MD) and a control group.<BR><B>METHODS: </B>This case-control analytical study was conducted on 37 subjects with MD and 37 healthy subjects. Subfoveal CT (SCT), large choroidal vessel (LCV) layer thickness, and mean subfoveal LCV thickness/mean SCT ratio were measured using enhanced-depth imaging optical coherence tomography (EDI-OCT) in the eyes on the MD side (ipsilateral), the contralateral eyes, and the control group.<BR><B>RESULTS: </B>A statistically significant difference was observed in the mean SCT values between the ipsilateral and control groups after adjustment for age, sex, and migraine (p = 0.04). Moreover, there was a statistically significant difference between the mean subfoveal LCV thickness values and the mean subfoveal LCV thickness/mean SCT ratio between the ipsilateral and control groups (p = 0.006, and p < 0.001, respectively). Patients with a duration of disease over three years had a greater mean subfoveal LCV thickness/mean SCT ratio (67.35 ± 11.56 and 60.66 ± 11.27, respectively), which was statistically insignificant (p = 0.08).<BR><B>CONCLUSIONS: </B>We found a thicker choroid and Haller layer, and a greater subfoveal LCV thickness/SCT ratio on the MD side compared to the controls. Furthermore, patients with a greater duration of disease had a lower subfoveal LCV thickness/SCT ratio. These findings may reflect the role of the trigeminal vascular system (TVS) and neurovascular pathophysiology in MD patients. More extensive studies are required to reach more definitive conclusions about the association between CT and MD.<BR><B>METHODS: </B>4 Laryngoscope, 134:1889-1893, 2024.