{Reference Type}: Journal Article
{Title}: Synthesis, Crystal Structure and Fluorimetric Study of 2-phenylphthalazin-1(2H)-one: a Highly Selective Florescent Chemosensor for Detection of Fe3+ and Fe2+ Metal Ions.
{Author}: Sharif S;Shahbaz M;Şahin O;Khurshid MA;Anbar MM;Dar B;
{Journal}: J Fluoresc
{Volume}: 0
{Issue}: 0
{Year}: 2023 Nov 1
{Factor}: 2.525
{DOI}: 10.1007/s10895-023-03484-w
{Abstract}: A ligand, 2-phenylphthalazin-1(2H)-one (K), was synthesized by refluxing 2-formylbenzoic acid with phenyl hydrazine in presence of ethanol. FTIR, elemental analysis and single crystal XRD techniques were used to elucidate the structure. Fluorimetric turn-off response was recorded when solution of ligand (K) in DMF was treated with aqueous solution of Fe3+ and Fe2+ metal ions. No specific changes were observed on addition of other metal ions (Pb2+, Cd2+, Mn2+, Zn2+, Ba2+, Ni2+, Al3+, Ag1+, Co2+, Ca2+, Cu2+, Mg2+, Cr3+). Limit of Detection (LOD) was calculated for Fe2 and Fe3+as 2.4 µM and 2.5µM respectively, which is quite below to the recommended value 5.4 µM of the Environment Protection Agency of USA. Association constants for Fe3+ and Fe2+ metal ions were determined as 6 × 10-4 M-1 and 3.6 × 10-4 M-1 respectively. Benesi-Hildebrand plot confirmed 1:1 binding ratio between metal ions and ligand.