{Reference Type}: Journal Article {Title}: Global genomic diversity and conservation of SARS-CoV-2 since the COVID-19 outbreak. {Author}: Li H;Ding L;Liao R;Li N;Hong X;Jiang Z;Liu D; {Journal}: Microbiol Spectr {Volume}: 11 {Issue}: 6 {Year}: 2023 Dec 12 {Factor}: 9.043 {DOI}: 10.1128/spectrum.02826-23 {Abstract}: OBJECTIVE: Our results indicate that most severe acute respiratory syndrome coronavirus 2 genomes sampled from patients had a mutation rate ≤1.07 ‰ and genome-tail proteins (including S protein) were the main sources of genetic polymorphism. The analysis of the virus-host interaction network of genome-tail proteins showed that they shared some antiviral signaling pathways, especially the intracellular protein transport pathway.