{Reference Type}: Journal Article
{Title}: Eyelid and conjunctival mast cell tumors: A retrospective study of 26 dogs and 8 cats.
{Author}: Fischer BM;Kessler M;Braus BK;
{Journal}: Vet Ophthalmol
{Volume}: 27
{Issue}: 3
{Year}: 2024 May 30
{Factor}: 1.444
{DOI}: 10.1111/vop.13152
{Abstract}: <B>OBJECTIVE: </B>The objective of the study was to describe clinical and histologic characteristics of eyelid (LMCT) and conjunctival (CMCT) mast cell tumors in dogs and cats presented to a referral clinic in Germany.<BR><B>METHODS: </B>Medical records were reviewed to identify dogs and cats diagnosed with LMCTs or CMCTs between 2006 and 2020.<BR><B>RESULTS: </B>LMCT were diagnosed in 31 patients and were cutaneous (n = 28; 20 dogs and 8 cats) or subcutaneous (three dogs). Five cases involved the mucocutaneous junction (four dogs, one cat). CMCTs occurred only in dogs (n = 3). At the time of presentation two of the four canine LMCT cases involving the mucocutaneous junction had metastasized to a mandibular lymph node. When applying the Kiupel system, both these cases were categorized as high grade. 85.7% (18/21) of the canine (19 cutaneous and 2 subcutaneous) LMCT and all CMCT cases were categorized as Kiupel low grade. No local recurrences occurred in all LMCT cases in which clean surgical margins were obtained (n = 18, mean surgical margin width: dogs 9.4 mm, cats 3.8 mm). Two cats (2/4) and four dogs (4/7) with questionable or incomplete surgical margins experienced local recurrences (mean time to recurrence of 180 and 637 days in dogs and cats, respectively).<BR><B>CONCLUSIONS: </B>Recurrence of low-grade LMCTs and CMCTs following excision with clean margins is rare. Tumors involving the mucocutaneous junction may be of higher grade and prone to lymphatic metastasis.