{Reference Type}: Review
{Title}: Ameloblastic fibro-dentinoma: a rare mixed odontogenic tumor case report with review of literature.
{Author}: Darwish NMA;Amer HWA;Mahrous NNM;
{Journal}: J Egypt Natl Canc Inst
{Volume}: 35
{Issue}: 1
{Year}: 2023 Oct 30
暂无{DOI}: 10.1186/s43046-023-00193-0
{Abstract}: <B>BACKGROUND: </B>Ameloblastic fibro-dentinoma is considered a rare, benign, mixed odontogenic tumor that occurs mainly in the posterior mandible in the 1st-2nd decade of life. Although the clinical behavior of Ameloblastic fibro-dentinoma is similar to that of ameloblastic fibroma, there is a debate about whether Ameloblastic fibro-dentinoma is a developing hamartomatous odontoma or a separate neoplastic odontogenic tumor like ameloblastic fibroma. However, it is important to understand the histopathogenesis of this rare tumor.<BR><B>METHODS: </B>A case report presenting an 11-year-old male child with a swelling in the posterior mandible. Radiographic examination revealed a multilocular lesion with mixed radiodensity related to the impacted lower left second premolar tooth. Incisional biopsy was done, and microscopic examination revealed cords and nests of odontogenic follicles lined by ameloblast-like cells and central stellate reticulum-like cells in the primitive ecto-mesenchymal stroma with areas of dentinoid material and osteodentin. The diagnosis was ameloblastic fibro-dentinoma. Surgical excision of the lesion was done, and the patient was followed up for 1 year without evidence of recurrence.<BR><B>CONCLUSIONS: </B>Reporting such a rare entity clarifies the debate about its nature and the importance of early diagnosis of lesions that are associated with unerupted teeth showing how it is effective in early management and prognosis.