{Reference Type}: Journal Article
{Title}: Haplosufficiency of MHCII in autoreactive germinal center B cells.
{Author}: Fahlquist-Hagert C;Wittenborn TR;Ferapontov A;Jensen L;Terczyńska-Dyla E;Degn SE;
{Journal}: Eur J Immunol
{Volume}: 54
{Issue}: 1
{Year}: 2024 Jan 24
{Factor}: 6.688
{DOI}: 10.1002/eji.202350422
{Abstract}: Utilizing an autoimmune bone marrow chimera model we determined that B cells depend critically on MHCII expression for participation in the germinal center, but cells displaying a 50% reduction in surface MHCII compete efficiently with their wild-type counterparts. This provides insights into the requirements for germinal center participation.