{Reference Type}: Case Reports
{Title}: Classical Hodgkin Lymphoma on the Background of Castleman Disease: A Case Report.
{Author}: Ma'koseh M;Al-Ibraheem A;Almasri N;Hamed E;Alrabi K;
{Journal}: Cureus
{Volume}: 15
{Issue}: 9
{Year}: 2023 Sep
暂无{DOI}: 10.7759/cureus.44930
{Abstract}: Castleman disease (CD) is a rare lymphoproliferative disorder that is associated with an increased risk for lymphoma. The association between CD and classical Hodgkin lymphoma (HL) is rare. The patient described here is a 44-year-old, HIV-seronegative male who presented with significant weight loss, fever, night sweats, and right axillary swelling. Imaging showed bulky infraclavicular, subpectoral, and axillary lymph nodes. A biopsy revealed classical HL on the background of a human herpesvirus-8 (HHV-8)-negative plasma cell variant of CD. The patient had a complete remission after six cycles of doxorubicin, bleomycin, vincristine, and dacarbazine (ABVD) that were followed by consolidative radiotherapy and continued to be disease-free for more than two years.