{Reference Type}: Case Reports
{Title}: Solitary acrometastasis of the phalanx as initial presentation of an oligometastatic Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma: a case report.
{Author}: Pușcașu AI;Moinard-Butot F;Antoni D;Schott R;Somme L;
{Journal}: J Med Case Rep
{Volume}: 17
{Issue}: 1
{Year}: 2023 Sep 18
暂无{DOI}: 10.1186/s13256-023-04127-1
{Abstract}: <B>BACKGROUND: </B>Acrometastasis is an uncommon finding in non-small cell lung cancer and is usually a sign of multimetastatic disease. Few case reports have suggested solitary digital metastasis as the single secondary lesion of oligometastatic non-small cell lung cancer.<BR><B>METHODS: </B>This case report describes an unusual presentation of a Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma with a solitary bone metastasis in the fourth finger medial phalanx, which was also the first sign of the disease, in a 63-year-old Caucasian female patient. Digital surgical amputation was performed. After histopathological confirmation and radiological exclusion of other secondary lesions, chemoimmunotherapy in a first-line setting was initiated. A partial metabolic response in the primary lung lesion was observed after four cycles. Maintenance therapy is currently being continued.<BR><B>CONCLUSIONS: </B>Solitary digital metastasis is a rare finding in non-small cell lung cancer. Further studies are needed to investigate the mechanisms behind this particular dissemination process.