{Reference Type}: Case Reports {Title}: A fatal case of hemophagocytic lymphohistiocytosis due to neonatal lupus erythematosus. {Author}: Mazori DR;Kleitsch J;Kabir S;Uwakwe LN;Glick SA; {Journal}: Pediatr Dermatol {Volume}: 41 {Issue}: 1 {Year}: 2024 Jan-Feb 4 {Factor}: 1.997 {DOI}: 10.1111/pde.15408 {Abstract}: Neonatal lupus erythematosus (NLE) is an autoimmune disease caused by the passive transfer of autoantibodies from mother to child during pregnancy. A rare complication of NLE is hemophagocytic lymphohistiocytosis (HLH), a potentially life-threatening hyperinflammatory state more commonly associated with other rheumatologic disorders. Herein, we describe a fatal case of NLE-associated HLH.