{Reference Type}: Journal Article
{Title}: Semaphorins in immune cell function, inflammatory and infectious diseases.
{Author}: Thomas R;Yang X;
{Journal}: Curr Res Immunol
{Volume}: 4
{Issue}: 0
{Year}: 2023
暂无{DOI}: 10.1016/j.crimmu.2023.100060
{Abstract}: The Semaphorin family is a group of proteins studied broadly for their functions in nervous systems. They consist of eight subfamilies ubiquitously expressed in vertebrates, invertebrates, and viruses and exist in membrane-bound or secreted forms. Emerging evidence indicates the relevance of semaphorins outside the nervous system, including angiogenesis, cardiogenesis, osteoclastogenesis, tumour progression, and, more recently, the immune system. This review provides a broad overview of current knowledge on the role of semaphorins in the immune system, particularly its involvement in inflammatory and infectious diseases, including chlamydial infections.