{Reference Type}: Journal Article
{Title}: Quality of life after wearing multifocal contact lenses for myopia control for 2 weeks in the BLINK Study.
{Author}: Ticak A;Walline JJ;Berntsen DA;Mutti DO;Jones-Jordan LA;Cardenas L;Day E;Dougherty BE; ;
{Journal}: Ophthalmic Physiol Opt
{Volume}: 43
{Issue}: 6
{Year}: 2023 Nov 23
{Factor}: 3.992
{DOI}: 10.1111/opo.13216
{Abstract}: <B>OBJECTIVE: </B>To validate Pediatric Refractive Error Profile 2 (PREP2) subscales that can be used to evaluate contact lens wearers and compare vision-specific quality of life measurements between children wearing multifocal and single vision contact lenses for 2 weeks.<BR><B>METHODS: </B>Two hundred and ninety-four myopic children aged 7-11 years (inclusive) were enrolled in the 3-year, double-masked Bifocal Lenses In Nearsighted Kids (BLINK) Study. Participants completed the PREP2 survey after having worn contact lenses for 2 weeks. The Vision, Symptoms, Activities and Overall PREP2 subscales were used to compare participants' subjective assessment while wearing +1.50 or +2.50 D add multifocal or single vision contact lenses. Rasch analysis was used to validate each subscale and to compare participants' subjective assessment of contact lens wear.<BR><B>RESULTS: </B>Item fit to the Rasch model was good for all scales, with no individual items having infit mean square statistics outside the recommended range (0.7-1.3). Response category function was acceptable for all subscales, with ordered category thresholds. Measurement precision, assessed by the Rasch person reliability statistic, was less than ideal (≥0.8) for three of the subscales, but met the minimum acceptable standard of 0.5. Scores for the Vision subscale differed by treatment assignment (p = 0.03), indicating that participants with the highest add power reported statistically worse quality of vision, although the difference was only 3.9 units on a scale of 1-100. Girls reported fewer symptoms than boys (p = 0.006), but there were no other differences between boys and girls.<BR><B>CONCLUSIONS: </B>Rasch analysis demonstrates that the PREP2 survey is a valid instrument for assessing refractive error-specific quality of life. These results suggest that vision-related quality of life is not meaningfully affected by 2 weeks of soft multifocal contact lens wear for myopia control.