{Reference Type}: Case Reports {Title}: A primary amoebic meningoencephalitis case associated with swimming in seawater. {Author}: Wang F;Shen F;Dai W;Zhao J;Chen X;Liu J; {Journal}: Parasitol Res {Volume}: 122 {Issue}: 10 {Year}: 2023 Oct 9 {Factor}: 2.383 {DOI}: 10.1007/s00436-023-07934-z {Abstract}: This case report describes a 62-year-old male fisherman who presented with persistent vomiting, headache, and behavior changes. Despite initial antibiotic and corticosteroid treatment, his condition worsened, leading to coma and subsequent death. Macro-genome sequencing of cerebrospinal fluid (CSF) revealed the presence of Naegleria fowleri infection, which had been missed during initial laboratory tests. The patient's exposure history included sea-swimming near Zhoushan Island.