{Reference Type}: Review {Title}: Can a diagnosis of Leiomyosarcoma soft palate be missed in the era of commoner oral carcinomas? - Rare case report and review of literature. {Author}: Kumar N;Gothwal RS;Lakhera KK;Chatterjee A;Singh S;Sharma RG;Patel P; {Journal}: J Cancer Res Ther {Volume}: 19 {Issue}: 3 {Year}: 2023 Apr-Jun {Factor}: 1.331 {DOI}: 10.4103/jcrt.jcrt_1024_21 {Abstract}: Leiomyosarcomas (LMSs) of the head and neck are an extremely rare entity. Of all smooth muscle tumors, 4%-10% occur in the head and neck and only 0.06% in the oral cavity. Because of its infrequency, it has been associated with both delayed diagnosis and misdiagnosis. Here, we report the clinicopathological findings of a case of primary LMS of the soft palate in a 42-year-old male patient with an emphasis on the judicious use of ancillary diagnostic modalities to arrive at a definitive diagnosis. Intraorally, LMSs present as painless, lobulated, fixed masses of the submucosal tissues in middle-aged or older individuals. The treatment modalities and lymph nodal dissection criteria are dissimilar to more common oral carcinomas. Hence, definitive diagnosis is necessary.