{Reference Type}: Case Reports
{Title}: A Rare Case of Neurosyphilis Manifesting as Psychosis in an HIV-Negative Patient.
{Author}: Yazigi A;Yazigi M;Zainah H;
{Journal}: Cureus
{Volume}: 15
{Issue}: 6
{Year}: 2023 Jun
暂无{DOI}: 10.7759/cureus.40064
{Abstract}: Neurosyphilis is a rare disease now, given the availability of antibiotics to treat syphilis. Patients with neurosyphilis could present with psychiatric symptoms. We present a rare case of neurosyphilis with only psychiatric symptoms. The patient was a 49-year-old male who presented with self-neglect and was not interacting with others. Treponema antibodies were positive, and rapid plasma reagin (RPR) was 1:512 with a positive venereal disease research laboratory test (VDRL) in the cerebrospinal fluid. The patient was treated with an IV penicillin regimen for neurosyphilis and improved remarkably with a return to baseline on follow-up.