{Reference Type}: Review
{Title}: The NLRP3 inflammasome in viral infection (Review).
{Author}: Zheng Q;Hua C;Liang Q;Cheng H;
{Journal}: Mol Med Rep
{Volume}: 28
{Issue}: 3
{Year}: 2023 Sep
{Factor}: 3.423
{DOI}: 10.3892/mmr.2023.13047
{Abstract}: The interplay between pathogen and host determines the immune response during viral infection. The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL‑1β, which play an important role in the innate immune responses. In the present review, the mechanisms of the NLR family pyrin domain containing 3 inflammasome activation and its dysregulation in viral infection were addressed.