{Reference Type}: Journal Article {Title}: The EANM guideline on radioiodine therapy of benign thyroid disease. {Author}: Campennì A;Avram AM;Verburg FA;Iakovou I;Hänscheid H;de Keizer B;Petranović Ovčariček P;Giovanella L; {Journal}: Eur J Nucl Med Mol Imaging {Volume}: 50 {Issue}: 11 {Year}: 2023 09 3 {Factor}: 10.057 {DOI}: 10.1007/s00259-023-06274-5 {Abstract}: This document provides the new EANM guideline on radioiodine therapy of benign thyroid disease. Its aim is to guide nuclear medicine physicians, endocrinologists, and practitioners in the selection of patients for radioiodine therapy. Its recommendations on patients' preparation, empiric and dosimetric therapeutic approaches, applied radioiodine activity, radiation protection requirements, and patients follow-up after administration of radioiodine therapy are extensively discussed.