{Reference Type}: Journal Article
{Title}: Generation of an iPSC line (TSHSUi001-A) from a patient with Peutz-Jeghers syndrome due to STK11 mutation.
{Author}: Wang T;Zhu K;Yu W;Peng L;Wang H;Wu Q;
{Journal}: Stem Cell Res
{Volume}: 71
{Issue}: 0
{Year}: 2023 09 22
{Factor}: 1.587
{DOI}: 10.1016/j.scr.2023.103152
{Abstract}: We established an iPSC line (TSHSUi001-A) from a patient with Peutz-Jeghers syndrome, carrying heterozygous c.290 + 1G > A mutation in STK11 gene. Peripheral blood mononuclear cells were reprogrammed using non-integrating delivery of OCT4, SOX2, KFL4, BCL-XL and c-MYC. The iPSC line expressed pluripotency markers, could differentiate into cells of three germ layers in vitro, and displayed a normal karyotype.