{Reference Type}: Case Reports
{Title}: Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition.
{Author}: Hanuna M;Pattathu J;Buech J;Kamla C;Kneidinger N;Behr J;Milger K;Veit T;Nagel M;Abicht J;Dalla-Pozza R;Fischer M;Jakob A;Hermann M;Schramm R;Rosenthal LL;Haas N;Hörer J;Hagl C;Michel SG;
{Journal}: Front Cardiovasc Med
{Volume}: 10
{Issue}: 0
{Year}: 2023
{Factor}: 5.846
{DOI}: 10.3389/fcvm.2023.1198204
{Abstract}: Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce. We describe two cases of CVC-related thrombosis (Hickman-catheter) complicated by recurrent pulmonary emboli. One patient experienced a complete thromboembolic obstruction of the right pulmonary artery with normal pulmonary pressures and the second patient suffered from a central thromboembolic obstruction of both pulmonary arteries associated with severe pulmonary hypertension. Both patients successfully underwent surgical thromboendarterectomy with deep hypothermic circulatory arrest.