{Reference Type}: Journal Article {Title}: Atherogenic Dyslipidemias: Unmet Needs and the Therapeutic Potential of Emerging and Novel Approaches and Drugs. {Author}: Romandini A;Baldassarre D;Genovese S;Capri S;Pompilio G;Scatigna M;Werba JP; {Journal}: Pharmaceuticals (Basel) {Volume}: 16 {Issue}: 2 {Year}: 2023 Jan 24 {Factor}: 5.215 {DOI}: 10.3390/ph16020176 {Abstract}: Innovative lipid-modifying agents are valuable resources to improve the control of atherogenic dyslipidemias and reduce the lipid-related residual cardiovascular risk of patients with intolerance or who are not fully responsive to a consolidated standard of care (statins plus ezetimibe). Moreover, some of the upcoming compounds potently affect lipid targets that are thus far considered "unmodifiable". The present paper is a viewpoint aimed at presenting the incremental metabolic and cardiovascular benefits of the emerging lipid-modulating agents and real-life barriers, hindering their prescription by physicians and their assumption by patients, which need to be worked out for a more diffuse and appropriate drug utilization.