{Reference Type}: Journal Article {Title}: ICTV Virus Taxonomy Profile: Poxviridae 2023. {Author}: McInnes CJ;Damon IK;Smith GL;McFadden G;Isaacs SN;Roper RL;Evans DH;Damaso CR;Carulei O;Wise LM;Lefkowitz EJ; {Journal}: J Gen Virol {Volume}: 104 {Issue}: 5 {Year}: 2023 05 {Factor}: 5.141 {DOI}: 10.1099/jgv.0.001849 {Abstract}: Poxviridae is a family of enveloped, brick-shaped or ovoid viruses. The genome is a linear molecule of dsDNA (128-375 kbp) with covalently closed ends. The family includes the sub-families Entomopoxvirinae, whose members have been found in four orders of insects, and Chordopoxvirinae, whose members are found in mammals, birds, reptiles and fish. Poxviruses are important pathogens in various animals, including humans, and typically result in the formation of lesions, skin nodules, or disseminated rash. Infections can be fatal. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Poxviridae, which is available at ictv.global/report/poxviridae.